THE EFFECTS OF CHLOROQUINE, PARACETAMOL AND PROMETHAZINE ON THE PHARMACOKINETICS OF CHLORPROPAMIDE IN HUMAN VOLUNTEERS

CHAPTER ONE INTRODUCTION 1.1 Pharmacokinetics Pharmacokinetics is the study of the time course of drug and metabolite levels in different fluids, tissues, and excreta of the body, and of the mathematical relationships required to develop models to interpret such data (Gibaldi and Perrier, 2004). Neligan (2006) defined Pharmacokinetics as the study of what the body … Read more

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